Yes, in fact Jesus had four brothers James, Joseph, Simon, and Judas (not the Judas who betrayed him) and a number of sisters’ which the Bible does not name. If you wanted to get technical, I guess you could call them His half- brothers and sisters. Read the story of Jesus’s return to His hometown of Nazareth.
53When Jesus finished teaching with these stories, he left there. 54He went to the town where he grew up. He taught the people in the synagogue, and they were amazed. They said, “Where did this man get such wisdom and this power to do miracles? 55 Isn’t he just the son of the carpenter we know? Isn’t his mother’s name Mary, and aren’t his brothers James, Joseph, Simon, and Judas? 56And don’t all his sisters still live here in town? How is he able to do these things?” 57So they had a problem accepting him. Matthew 13:55-56 (ERV)
The Apostle Paul met Jesus’ brother, James, in Jerusalem.
18Three years later I went to Jerusalem to meet Peter. I stayed with him 15 days. 19I met no other apostles—only James, the brother of the Lord. Galatians 1:18-19 (ERV)